1 natijalarini 12-15 Ko'rsatilgan

CAS NO. MAHSULOT NOMI Umumiy
    607737-87-1 A77-01 (607737-87-1)

    77-01 kuchli TGF-RRI (ALK-5) inhibitori (IC50 = 34 nM). TGF-b transkripsiyadan foydalanishni inhibe qiladi. TGF-b induktsiyasining proliferatsiyasini inhibe ...

    909910-43-6 A83-01 (909910-43-6)

    A 83-01 - TGF-b I I retseptorlari ALK5 kinazining kuchli inhibitori, ALK4 turi I ning aktiv / nodal retseptorlari va ALK7 tipidagi I nodal retseptorlari.

    1206711-16-1 DMH1 (1206711-16-1)

    DMH1 - ALXINUMX uchun 50 nM ning IC107.9 bilan tanlab olingan BMP retseptorlari inhibitori bo'lib, AMPK, ALK2, KDR (VEGFR-5) yoki PDGFR da hech qanday inhibisyon ko'rsatmaydi.

    1352608-82-2 EW-7197 (1352608-82-2)

    Vaktosertib - bu o'sish omilini (TGF) -beta retseptorlari turi 1 (TGFBR1 ...) o'zgartiradigan, serine / treonin kinazning og'zaki ravishda biologik mavjud bo'lgan inhibitori.

    864082-47-3 GSK429286A (864082-47-3)

    GSK429286A 1 nM va 2 nM ning IC50 bilan navbati bilan ROCK14 va ROCK63ning selektiv inhibitori. GSK429286A - tanlangan bir Rho-kinaza inhibi ...

    1431985-92-0 K02288 (1431985-92-0)

    K02288 - BMP signalizatsiyasi kuchli inhibitori. K02288 ning kamroq nanomoliy kontsentratsiyalarda ALK2 ning in vitro faolligi bor.

    1432597-26-6 LDN-212854 (1432597-26-6)

    LDN-212854 - suyak morfogenetik oqsili (BMP) I-retseptorlari kinazlarining selektiv va kuchli inhibitori bo'lib, 5,000-qavatdagi selektivi ...

    1062368-24-4 LDN193189 (1062368-24-4)

    LDN193189 50 ning IC5 va 30 nM ning ALK2 va ALK3 uchun yuqori kuchli kuchli kichik BMP inhibitori. LDN193189 da B ni inhibe ...

    700874-71-1 LY2109761 (700874-71-1)

    LY2157299 - TGF-b retseptorlari turi 1 / II turdagi kinazlarning (IC50 = 69 nM) kichik molekula inhibitori .1 T. rolini o'rganish uchun ishlatilgan.

    1062368-49-3 ML347 (1062368-49-3)

    LDN347 sifatida ham tanilgan ML-193719, ALK1 va ALK2 ni inhibe qiluvchi kuchli va tanlanadigan suyak morfogenetik protein retseptorlari (BMP) inhibitori ...

    446859-33-2 RepSox (446859-33-2)

    SJN 2511, E 616452 va ALK5 inhibitori sifatida ham tanilgan RepSox, TGF-b tipidagi 1 aktivlarining hujayra o'tkazuvchan, tanlangan inhibitori bo'lib, ...

    301836-41-9 SB431542 (301836-41-9)

    SB-431542 - bu insonning malign glioma hujayralari sathining panelida, I turdagi TGF-beta retseptorining yangi kichik molekula inhibitori.

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