1 natijalarini 12-36 Ko'rsatilgan

CAS NO. MAHSULOT NOMI Umumiy
    856925-71-8 (-) - Blebbistatin (856925-71-8)

    (-) - Blebbistatin nekrozsiz miyosin II ATPaz uchun xNUMXmX dan IC50 bilan hujayra-o'tkazuvchan inhibitordir, myozinning engil zanjirli kinazini inhibe qilmaydi ...

    1268524-70-4 (+) - JQ1 (1268524-70-4)

    (+) - JQ1 - BET bromodomain inhibitori, BRD50 (77 / 33) uchun 4 nM / 1 nM ning IC2 bilan, BET oilasining barcha bromodomenleriga bog`langan, ammo bromga emas.

    659730-32-2 AMG517 (659730-32-2)

    AMG 517 kuchli va tanlangan TRPV1 antagonisti, kappaitsin, proton va XPN1 ning 50 nM, 0.76 nM ning IC0.62 bilan issiqlik faollashuvi ...

    401900-40-1 Andarine (401900-40-1)

    Andarine anabolik organlar uchun to'qimalarni tanlaydigan 4 nM dan Ki bilan tanlanadigan steroid bo'lmagan androgen retseptorlari (AR) agonistidir ....

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    1233339-22-4 AZ20 (1233339-22-4)

    AZ20 - ATX kinazining kuchli va selektiv inhibitori, ICNNMXX ning 50 nM, mTOR orqali 5-qavatni tanlash. AZ8 - ATR protein kinaz i ...

    1821428-35-6 AZD0156 (1821428-35-6)

    AZD0156 - og'iz, kuchli va selektiv ATM kinaz inhibitori, ATM ning kinaza faolligini va ATM vositachiligida signalizatsiyani oldini oladi, D ...

    1240299-33-5 AZD3514 (1240299-33-5)

    AZD3514 kuchli va og'iz androgen retseptorlari pastki regulyatori bo'lib, Ki ning 2.2 ìMand bilan AR proteinli ekspressini kamaytirish qobiliyatiga ega ...

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    1035270-39-3 AZD4547 (1035270-39-3)

    AZD4547 - FGFR1 / 2 / 3 ni xNUMX nM / 50 nM / 0.2 nM ning IC2.5 bilan belgilaydigan yangi FGFR inhibitori, FGFR1.8, VEGFR4 (KDR) ga nisbatan zaifroq faoliyat ...

    1352226-88-0 AZD6738 (1352226-88-0)

    AZD6738 kuchli ATR inhibitori. 1 ning IC345 qiymati bo'lgan kameralarda ATR substratining Chk50 Ser74 fosforilatsiyasini inhibe qilishi mumkin ...

    860352-01-8 AZD7762 (860352-01-8)

    AZD7762 1 nM ning IC50 bilan kuchli va tanlangan bir Chk5 inhibitori. Chk2 ga nisbatan kam kuchliroq va kamroq CAMga qarshi, ha, Fy ...

    847499-27-8 CEP-18770 (Delanzomib) (847499-27-8)

    CEP-18770 - proteazomning ximotripsinga o'xshash faoliyati 50 nM IC3.8 bilan og'iz orqali faol inhibitori bo'lib, faqatgina marginal inhibitatsiya bilan ...

    905973-89-9 CGK733 (905973-89-9)

    CGK 733 ATM / ATR ning kuchli va tanlangan inhibitori bo'lib, IC50 ning ~ 200 nM dan iborat. CGK733 - ATM inhibitori va ATR inhibitori, bu esa ...